We recommend spending at least two days in Prague, preferably three, before considering a trip out of town. If you have the time, take a day trip or even an overnight trip to enjoy a different part of the Czech Republic and to see the countryside, villages and small towns outside of Prague.
Day Trips from Prague
Kutná Hora, Karlštejn Castle, Karlovy Vary, Tábor, Olomouc, Dresden (Germany)
Overnight Trips from Prague
Český Krumlov, Bohemian Paradise, Brno
Trips from Prague to Neighboring Countries
Vienna, Salzburg, Berlin, Frankfurt, Munich, Kraków, Warsaw, Bratislava, Budapest